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. 2025 Jun 16;16:1522759. doi: 10.3389/fendo.2025.1522759

Table 2.

Clinical information from the eligible trials in the meta-analysis.

Included studies Dosage of TSF Intervention period Intervening methods Control group regimens Parameter types Reference
Wang T 2013 8 grams TSF, twice daily 24 weeks TSF VS Con placebo glycosylated hemoglobin (HbA1c),24-hour total urine protein (24-hTP) (19)
Yang H 2024 8 grams TSF, twice daily 24 weeks TSF VS Con placebo hemoglobin A1c (HbA1c), albumin-to-creatinine ratio (UACR) levels,8-hydroxy-2′-deoxyguanosine (8-OHdG), 3-nitrotyrosine (3-NT), the enzymic anti-oxidant, superoxide dismutase (SOD) (20)
Yang X 2016 8 grams TSF, twice daily 24 weeks TSF VS Con placebo Scr (μmol/L),24 h UP (g/24 h),eGFR (ml/min/1.73 m2),
In plasma L-FABP (μg/ml)
(21)
Li P 2015 8 grams TSF, twice daily 24 weeks TSF VS Con placebo ORR,AE,UAER (μg/min),Scr (μmol/L),24 h UP (g/24 h),eGFR (ml/min/1.73 m2),BUN (mmol/L) (22)

Scr (μmol/L), Serum Creatinine; 24 h UP (g/24 h), 24-Hour Urine Protein; eGFR, Estimated Glomerular Filtration Rate; ORR, Objective Response Rate; AE, Adverse Event; UAER, Urine Albumin Excretion Rate; BUN, Blood Urea Nitrogen; L-FABP, Liver Fatty Acid Binding Protein.

Meta-analyses of Chinese herbal medicine Formula treatment with diabetic kidney disease.