Table 6.
Results from the univariate and multivariate Cox proportional hazard models.
| Variables | Univariate | Multivariate | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| β | S. E | Z | p | HR (95%CI) | β | S. E | Z | p | HR (95%CI) | |
| Gender | ||||||||||
| F | 1.00 (Reference) | |||||||||
| M | −0.10 | 0.09 | −1.07 | 0.284 | 0.91 (0.76–1.08) | |||||
| Admission Age | −0.00 | 19.39 | −0.00 | 1.000 | 1.00 (0.00–32030507569812488.00) | |||||
| Sofa Score | 0.04 | 0.01 | 3.03 | 0.002 | 1.04 (1.02–1.07) | 0.03 | 0.02 | 1.58 | 0.113 | 1.03 (0.99–1.06) |
| APSIII | 0.01 | 0.00 | 6.50 | <0.001 | 1.01 (1.01–1.01) | 0.01 | 0.00 | 3.67 | <0.001 | 1.01 (1.01–1.01) |
| Creatinine | 0.02 | 0.02 | 0.81 | 0.416 | 1.02 (0.97–1.06) | |||||
| Alt | −0.00 | 0.00 | −0.96 | 0.336 | 1.00 (1.00–1.00) | |||||
| Ast | −0.00 | 0.00 | −0.88 | 0.379 | 1.00 (1.00–1.00) | |||||
| Bilirubin total | 0.01 | 0.01 | 2.89 | 0.004 | 1.01 (1.01–1.03) | 0.00 | 0.01 | 0.23 | 0.821 | 1.00 (0.99–1.01) |
| RBC | −0.15 | 0.06 | −2.65 | 0.008 | 0.86 (0.77–0.96) | −0.10 | 0.14 | −0.76 | 0.450 | 0.90 (0.69–1.18) |
| WBC | 0.01 | 0.00 | 2.99 | 0.003 | 1.01 (1.01–1.01) | 0.01 | 0.00 | 2.37 | 0.018 | 1.01 (1.01–1.01) |
| Platelet | 0.00 | 0.00 | 0.70 | 0.482 | 1.00 (1.00–1.00) | |||||
| Hemoglobin | −0.05 | 0.02 | −2.41 | 0.016 | 0.95 (0.92–0.99) | 0.01 | 0.05 | 0.12 | 0.903 | 1.01 (0.92–1.11) |
| Heart Rate | −0.00 | 0.00 | −0.05 | 0.960 | 1.00 (1.00–1.00) | |||||
| Resp Rate | 0.01 | 0.01 | 1.80 | 0.072 | 1.01 (1.00–1.02) | |||||
| Sbp | 0.00 | 0.00 | 1.67 | 0.094 | 1.00 (1.00–1.01) | |||||
| Dbp | 0.00 | 0.00 | 0.59 | 0.557 | 1.00 (1.00–1.01) | |||||
| Propofol ICU Used | ||||||||||
| No | 1.00 (Reference) | 1.00 (Reference) | ||||||||
| Yes | −0.37 | 0.12 | −2.99 | 0.003 | 0.69 (0.54–0.88) | −0.04 | 0.13 | −0.28 | 0.782 | 0.96 (0.75–1.25) |
| Dexmedetomidine ICU used | ||||||||||
| No | 1.00 (Reference) | 1.00 (Reference) | ||||||||
| Yes | −0.56 | 0.09 | −6.25 | <0.001 | 0.57 (0.48–0.68) | −0.49 | 0.09 | −5.27 | <0.001 | 0.61 (0.51–0.73) |
| Midazolam ICU used | ||||||||||
| No | 1.00 (Reference) | |||||||||
| Yes | −0.11 | 0.10 | −1.03 | 0.302 | 0.90 (0.73–1.10) | |||||
| Tramadol ICU used | ||||||||||
| No | 1.00 (Reference) | 1.00 (Reference) | ||||||||
| Yes | −1.62 | 0.34 | −4.80 | <0.001 | 0.20 (0.10–0.38) | −1.58 | 0.34 | −4.66 | <0.001 | 0.21 (0.11–0.40) |
| Congestive Heart Failure | ||||||||||
| No | 1.00 (Reference) | 1.00 (Reference) | ||||||||
| Yes | 0.19 | 0.09 | 2.10 | 0.035 | 1.21 (1.01–1.45) | 0.33 | 0.10 | 3.46 | <0.001 | 1.39 (1.16–1.68) |
| Cerebrovascular Disease | ||||||||||
| No | 1.00 (Reference) | |||||||||
| Yes | 0.10 | 0.12 | 0.86 | 0.390 | 1.11 (0.88–1.40) | |||||
| Chronic Pulmonary Disease | ||||||||||
| No | 1.00 (Reference) | |||||||||
| Yes | 0.10 | 0.10 | 0.97 | 0.331 | 1.10 (0.91–1.33) | |||||
| Diabetes | ||||||||||
| No | 1.00 (Reference) | |||||||||
| Yes | −0.05 | 0.10 | −0.48 | 0.632 | 0.95 (0.79–1.15) | |||||
| Renal Disease | ||||||||||
| No | 1.00 (Reference) | |||||||||
| Yes | 0.12 | 0.10 | 1.20 | 0.231 | 1.13 (0.93–1.38) | |||||
| Malignant Cancer | ||||||||||
| No | 1.00 (Reference) | |||||||||
| Yes | 0.14 | 0.14 | 1.02 | 0.307 | 1.15 (0.88–1.51) | |||||
| Metastatic Solid Tumor | ||||||||||
| No | 1.00 (Reference) | 1.00 (Reference) | ||||||||
| Yes | 0.83 | 0.18 | 4.65 | <0.001 | 2.28 (1.61–3.23) | 0.71 | 0.18 | 3.90 | <0.001 | 2.03 (1.42–2.90) |
| Vasoactive | ||||||||||
| No | 1.00 (Reference) | |||||||||
| Yes | 0.25 | 0.13 | 1.93 | 0.054 | 1.28 (1.00–1.65) | |||||