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Changes in the physicochemical properties of the mRNA-LNPs during storage period
| Storage time (week) | Size | DPI | Zeta potential | EE% |
|---|---|---|---|---|
| 0 | 81.72 | 0.074 | -5.83 | 68.73 |
| 1 | 81.62 | 0.074 | -5.27 | 68.00 |
| 2 | 82.15 | 0.072 | -2.41 | 66.26 |
| 3 | 83.44 | 0.070 | 0.66* | 64.14 |
| 4 | 84.83 | 0.070 | 7.15* | 63.32 |
Data are the average values of three replicates corresponding to each storage time. The significant difference (P<0.05) shown with asterisk.
