TABLE 2.
Prevalence of and adjusted associations between cardiometabolic disease and type 2 biomarkers
| Blood eosinophils | F ENO | IgE | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Low (n=3431) | Elevated (n=826) | p-value | Low (n=2703) | Elevated (n=690) | p-value | Non-sensitised (n=3123) | Sensitised (n=1086) | p-value | |
| Prevalence | |||||||||
| Diabetes | 111 (3.2) | 66 (8.0) | <0.001 | 102 (3.8) | 35 (5.1) | 0.12 | 127 (4.1) | 48 (4.4) | 0.61 |
| CVD | 72 (2.1) | 34 (4.1) | 0.001 | 57 (2.1) | 23 (3.3) | 0.06 | 73 (2.3) | 30 (2.8) | 0.43 |
| Hypertension | 684 (19.9) | 240 (29.1) | <0.001 | 591 (21.9) | 155 (22.5) | 0.73 | 696 (22.3) | 216 (20.1) | 0.13 |
| Adjusted# estimate (OR (95% CI)) | |||||||||
| Diabetes | 1 | 2.07 (1.54–2.78) | 1 | 1.20 (0.81–1.78) | 1 | 1.12 (0.81–1.55) | |||
| CVD | 1 | 1.70 (1.16–2.50) | 1 | 1.23 (0.76–2.00) | 1 | 1.17 (0.78–1.75) | |||
| Hypertension | 1 | 1.43 (1.21–1.69) | 1 | 0.91 (0.74–1.12) | 1 | 0.94 (0.79–1.11) | |||
Data are presented as n (%), unless otherwise stated. CVD: cardiovascular disease. #: adjusted for sex, age, body mass index and smoking history.