TABLE 3.
Odds ratios# (95% CIs) for cardiometabolic disease among participants with different combinations of elevated type 2 biomarkers
| Diabetes | CVD | Hypertension | |
|---|---|---|---|
| Elevated blood eosinophils | 1.63 (1.02–2.59) | 1.90 (1.02–3.55) | 1.58 (1.23–2.04) |
| Elevated FENO | 0.47 (0.20–1.10) | 2.48 (1.31–4.70) | 0.95 (0.70–1.29) |
| IgE sensitisation | 0.97 (0.56–1.69) | 1.69 (0.87–3.28) | 1.15 (0.89–1.48) |
| Blood eosinophils and FENO elevated | 2.79 (1.46–5.32) | 2.04 (0.77–5.41) | 1.36 (0.88–2.09) |
| Elevated blood eosinophils and IgE sensitisation | 1.69 (0.83–3.45) | 3.75 (1.76–7.97) | 1.35 (0.90−2.03) |
| Elevated FENO and IgE sensitisation | 1.24 (0.58–2.67) | 0.28 (0.04–2.07) | 0.86 (0.57–1.29) |
| All three biomarkers elevated | 3.39 (1.58–7.27) | 2.16 (0.63–7.38) | 1.23 (0.70–2.15) |
CVD: cardiovascular disease; FENO: exhaled nitric oxide fraction. #: adjusted for sex, age, body mass index and smoking history.