Table 2.

Recent guidelines and reviews on osteoporosis in men

Authors	Title	Highlights	Source
Bandeira et al	Male osteoporosis	Male osteoporosis screening and treatment focus on early detection through bone mineral density measurement and fracture risk assessment, alongside personalized interventions including pharmacologic treatments and lifestyle modifications to reduce fracture risk and improve bone health	Arch Endocrinol Metab. 2022;66:739–747
Beaudart C et al	Efficacy of osteoporosis pharmacological treatments in men	Systematic review and meta-analysis of pharmacological treatment effectiveness in male osteoporosis	Aging Clin Exp Res 2023;35:1789–1806
Björnsdottir S et al	Male osteoporosis-what are the causes, diagnostic challenges, and management	Screening and treatment for male osteoporosis emphasize the use of fracture risk assessment tools and bone density measurements, alongside individualized pharmacologic and nonpharmacologic interventions, to effectively reduce fracture risks and improve overall bone health in men	Best Pract Res Clin Rheumatol. 2022;36:101,766
Black DM et al	Treatment-related changes in bone mineral density as a surrogate biomarker for fracture risk reduction	Analysis of treatment efficacy markers in male osteoporosis, providing guidance for clinical decision-making	Lancet Diabetes Endocrinol 2020;8:672–682
Bouvard B et al	French recommendations for the management and treatment of male osteoporosis	Details French national guidelines for screening, diagnosis, and treatment of male osteoporosis, with focus on risk stratification and treatment selection	Rheum Rev 2021;88:173–182
Bruhn R et al	Epidemiology of male osteoporosis in Denmark (1996–2018)	Osteoporosis in men, often underdiagnosed and undertreated, affects nearly one in four men over 50, with increasing prevalence and treatment initiation rates, highlighting the need for improved fracture risk assessment, early diagnosis, and comprehensive management strategies	Osteoporos Int. 2023;34:935–942
Chandran M et al	The health and economic burden of osteoporotic fractures in Singapore	Analysis of osteoporosis burden and treatment strategies in Asian men, with recommendations for management approaches	Arch Osteoporos 2019;14:114
Fuggle NR et al	Evidence-based guideline for the management of osteoporosis in men	Comprehensive guideline addressing screening, diagnosis, and treatment approaches specific to male osteoporosis. Emphasizes the importance of risk assessment and individualized treatment plans	Nat Rev Rheumatol.2024;20:241–251
Gates M et al	Screening for the primary prevention of fragility fractures among adults aged 40 years and older in primary care: systematic reviews of the effects and acceptability of screening and treatment, and the accuracy of risk prediction tools	Male osteoporosis screening and treatment emphasize early risk assessment, utilizing tools like bone mineral density and fracture risk evaluation, alongside pharmacologic and lifestyle interventions, to effectively prevent fractures and improve skeletal health	Syst Rev. 2023;12:51
Gregson CL et al	UK clinical guideline for the prevention and treatment of osteoporosis	For male osteoporosis, the guidelines emphasize fracture risk assessment and intervention thresholds, focusing on men aged 50 and older, and recommend treatments such as antiresorptive and anabolic agents to provide a comprehensive approach to fracture prevention and management	Arch Osteoporos. 2022;17:58
Kanis JA et al	Algorithm for the management of patients at low, high and very high risk of osteoporotic fractures	Risk-stratified approach to osteoporosis management, including specific considerations for male patients	Osteoporos Int 2020;31:1–12
Keaveny TM et al	Osteoporosis treatment prevents hip fracture similarly in both sexes: the FOCUS observational study	For male osteoporosis, the guidelines emphasize fracture risk assessment and personalized treatment, demonstrating that osteoporosis treatments are equally effective in preventing fractures in both sexes and underscoring the need for increased focus on screening and management for men	J Bone Miner Res. 2024;39:1424–1433
Morin SN et al	Clinical practice guideline for management of osteoporosis and fracture prevention in Canada: 2023 update	For male osteoporosis, the focus is on fracture risk assessment and the implementation of both pharmacologic and nonpharmacologic interventions, with an emphasis on early detection and personalized treatment to prevent fractures and support skeletal health in men aged 50 and older	CMAJ. 2023;195:E1333-E1348
Narla RR et al	Rationale for osteoporosis screening in men	Targeted screening for male osteoporosis, particularly in high-risk groups, identifies men at fracture risk and enables timely interventions to reduce fractures and associated complications	Osteoporos Int. 2024 (In Press) 10.1007/s00198-024–07337-5
Sng GGR et al	Osteoporosis in men—east and west: can the twain meet? A perspective from Asia	Discusses the underdiagnosis and undertreatment of osteoporosis in men, highlighting disparities in BMD and treatment between Asian and Western populations. Evaluates the efficacy of screening tools and pharmacological treatments tailored for Asian men	Osteoporosis and Sarcopenia, 2024;10:131–144
Vilaca T et al	Osteoporosis in men	Osteoporosis in men, often overlooked, is diagnosed using the same criteria as in women, with management focusing on addressing secondary causes, lifestyle modifications, adequate calcium and vitamin D, exercise, and pharmacological treatments like bisphosphonates, denosumab, and teriparatide to increase bone mineral density and reduce fracture risks	Lancet Diabetes Endocrinol. 2022;10:273–283
Yu F et al	The epidemiology of osteoporosis, associated fragility fractures, and management gap in China	For Chinese men, osteoporosis screening and treatment emphasize early fracture risk assessment using tools such as bone mineral density measurement and individualized interventions, addressing the underdiagnosis and treatment gaps to prevent fractures and improve bone health	Arch Osteoporos. 2019;14:32