Table 1. Clinical characteristics, procedure-related data and geriatric profile in the whole cohort and according to the presence of clinical events during follow up.
| Whole population (n = 377) |
Patients with mortality or readmission (n = 110) |
Patients without events (n = 267) |
P-value | |
| Data are presented as mean ± SD or n (%). ADL: activities of daily living; IF-VIG: frailty index based on comprehensive geriatric assessment; MNA-SF: mini nutritional assessment-short form. | ||||
| Baseline clinical characteristics and procedure related data | ||||
| Age | 80.4 ± 6 | 80.2 ± 8 | 80.5 ± 5 | 0.819 |
| Male gender | 166 (44%) | 56 (50.9%) | 110 (41.2%) | 0.018 |
| Hypertension | 327 (88.6%) | 89 (84.8%) | 238 (90.2%) | 0.141 |
| Diabetes mellitus | 124 (33.6%) | 44 (41.9%) | 80 (30.3%) | 0.023 |
| Dyslipidiemia | 290 (78.6%) | 84 (80%) | 206 (78%) | 0.677 |
| Active smoking | 11 (2.9%) | 4 (3.6%) | 7 (2.6%) | 0.162 |
| Prior myocardial infarction | 26 (7%) | 12 (11.4%) | 14 (5.3%) | 0.044 |
| Prior PCI | 58 (15.7%) | 21 (20%) | 37 (14%) | 0.154 |
| Prior cardiac surgery | 26 (7%) | 6 (5.7%) | 20 (7.6%) | 0.528 |
| Atrial fibrillation | 95(25.2%) | 32 (29.1%) | 63 (23.6%) | 0.207 |
| Prior permanent pacemaker | 26 (7%) | 9 (8.6%) | 17 (6.4%) | 0.470 |
| Prior stroke | 24 (8.7%) | 9 (11.7%) | 15 (7.5%) | 0.267 |
| Peripheral artery disease | 43 (11.7%) | 15 (14.3%) | 28 (10.6%) | 0.326 |
| COPD | 39 (14.1%) | 13 (16.9%) | 26 (13%) | 0.405 |
| Chronic kidney disease | 137 (37.3%) | 43 (41%) | 94 (35.9%) | 0.364 |
| LEVF | 59% ± 9% | 59% ± 10%) | 59% ± 9% | 0.703 |
| Valve In valve | 12 (3.3%) | 2 (1.9%) | 10 (3.8%) | 0.283 |
| Pacemaker requirement | 65 (18.4%) | 24 (23.5%) | 41 (16.3%) | 0.110 |
| Geriatric assessment | ||||
| ADL (Barthel Index) | 0.283 | |||
| Independent | 232 (61.5%) | 63 (57.3%) | 169 (63.3%) | |
| Mildly dependent | 143 (37.9%) | 46 (41.8%) | 97 (36.3%) | |
| Instrumental activities (Lawton-Brody index) | 0.016 | |||
| Independent | 247 (65.5%) | 72 (65.5%) | 175 (65.5%) | |
| Mildly dependent | 92 (24.4%) | 23 (20.9%) | 69 (25.8%) | |
| Moderately dependent | 28 (7.4%) | 7 (6.4%) | 21 (7.9%) | |
| Severely dependent | 8 (2.1%) | 6 (5.5%) | 2 (0.7%) | |
| Completely dependent | 1 (0.3%) | 1 (0.9%) | 0 | |
| Cognitive impairment (Pfeiffer test) | 0.133 | |||
| None | 353 (93.6%) | 105 (95.5%) | 248 (92.9%) | |
| Mild or moderate | 23 (6.1%) | 4 (3.6%) | 19 (7.1%) | |
| Frailty (Fried criteria) | 125 (33.2%) | 42 (38.2%) | 83 (31.1%) | 0.183 |
| Frailty (FRAIL scale) | 67 (17.8%) | 21 (19.1%) | 46 (17.2%) | 0.384 |
| Frailty (IF-VIG) | 73 (19.5%) | 28 (25.7%) | 45 (17%) | 0.054 |
| Frailty (Essential Frailty Toolset) | 0.025 | |||
| 0-1 | 296 (80%) | 79 (74.5%) | 217 (82.2%) | |
| 2 | 59 (15.9%) | 19 (17.9%) | 40 (15.2%) | |
| 3 | 14 (3.8%) | 7 (6.6%) | 7 (2.7%) | |
| 4 | 1 (0.3%) | 1 (0.9%) | 0 | |
| Frailty (SPPB) | 183 (49.2%) | 62 (57.9%) | 121 (45.7%) | 0.032 |