Table 1. Clinical baseline data of the patients.
| Variables | All (n=219) | Non-MCE (n=152) | MCE (n=67) | P |
|---|---|---|---|---|
| Sex | 0.522 | |||
| Female | 96 (43.84) | 62 (40.79) | 34 (50.75) | |
| Male | 123 (56.16) | 90 (59.21) | 33 (49.25) | |
| Age (years) | 0.655 | |||
| ≤49 | 5 (2.28) | 4 (2.63) | 1 (1.49) | |
| 50–59 | 57 (26.03) | 36 (23.68) | 21 (31.34) | |
| 60–69 | 53 (24.2) | 35 (23.03) | 18 (26.87) | |
| 70–79 | 58 (26.48) | 43 (28.29) | 15 (22.39) | |
| ≥80 | 46 (21.01) | 34 (22.37) | 12 (17.91) | |
| Smoking | >0.999 | |||
| No | 139 (63.47) | 93 (61.18) | 46 (68.66) | |
| Yes | 80 (36.53) | 59 (38.82) | 21 (31.34) | |
| Alcohol | 0.523 | |||
| No | 157 (71.69) | 102 (67.11) | 55 (82.09) | |
| Yes | 62 (28.31) | 50 (32.89) | 12 (17.91) | |
| Hypertension | 0.172 | |||
| No | 89 (40.64) | 60 (39.47) | 29 (43.28) | |
| Yes | 130 (59.36) | 92 (60.53) | 38 (56.72) | |
| Diabetes | 0.692 | |||
| No | 151 (68.95) | 108 (71.05) | 43 (64.18) | |
| Yes | 68 (31.05) | 44 (28.95) | 24 (35.82) | |
| Hyperlipidemia | 0.102 | |||
| No | 159 (72.6) | 107 (70.39) | 52 (77.61) | |
| Yes | 60 (27.4) | 45 (29.61) | 15 (22.39) | |
| Atrial fibrillation | 0.162 | |||
| No | 133 (60.73) | 97 (63.82) | 36 (53.73) | |
| Yes | 86 (39.27) | 55 (36.18) | 31 (46.27) | |
| Heart failure | 0.313 | |||
| No | 98 (44.75) | 83 (54.61) | 15 (22.39) | |
| Yes | 121 (55.25) | 69 (45.39) | 52 (77.61) | |
| HMCAS | >0.999 | |||
| No | 160 (73.06) | 126 (82.89) | 34 (50.75) | |
| Yes | 59 (26.94) | 26 (17.11) | 33 (49.25) | |
| Massive stroke | 0.823 | |||
| No | 122 (55.71) | 109 (71.71) | 13 (19.4) | |
| Yes | 97 (44.29) | 43 (28.29) | 54 (80.6) | |
| Treatment | 0.243 | |||
| Non-reperfusion | 128 (58.45) | 81 (53.29) | 47 (70.15) | |
| IVT | 39 (17.81) | 32 (21.05) | 7 (10.45) | |
| MT | 36 (16.44) | 29 (19.08) | 7 (10.45) | |
| IVT with MT | 16 (7.30) | 10 (6.58) | 6 (8.95) | |
| Age, years | 69.07 (59.0, 78.0) | 69.89 (60.0, 78.25) | 67.19 (58.0, 76.0) | 0.119 |
| Stroke onset time, h | 8.71 (3.0, 12.0) | 8.84 (3.0, 12.0) | 8.41 (3.0, 11.0) | 0.728 |
| NIHSS score | 12.97 (8.0, 17.0) | 11.84 (7.0, 17.0) | 15.54 (12.0, 18.0) | <0.001* |
| Infarct volume, cm3 | 85.63 (24.41, 123.84) | 56.35 (13.61, 84.75) | 152.06 (95.6, 180.6) | <0.001* |
| ASPECTS | 6.71 (5.0, 8.0) | 7.38 (6.0, 9.0) | 5.21 (4.0, 7.0) | <0.001* |
Data are presented as n (%) or median (interquartile range). ASPECTS, Alberta Stroke Program Early Computed Tomography Score; HMCAS, hyperdense middle cerebral artery sign; IVT, intravenous thrombolysis; MCE, patients with malignant cerebral edema; MT, mechanical thrombectomy; NIHSS, National Institutes of Health Stroke Scale; Non-MCE, patients without malignant cerebral edema.