Table 1.
Timeline of enrollment, intervention, and assessment during the study period.
| Procedures | Study period | Post allocation | Close-out | |||||||||
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Enrollment | Preallocation | Allocation |
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| Time point | –t1 | Baseline | 0 | Post fight | 45 min post fight | Day 3 | Day 6 | 1 week post fight | ||||
| Enrollment | ✓ |
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Eligibility screen | ✓ |
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Informed consent | ✓ |
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Basic medical examination | ✓ |
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Allocation |
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✓ |
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| Interventions |
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Selective head and neck cooling (Aa) |
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✓ |
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Return to fight protocol (A+Bb) |
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✓ | ✓ | ✓ | ✓ |
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Collecting blood sample |
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✓ |
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✓ | ✓ | ✓ | ✓ |
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| Assessments (SCAT-5c) |
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SCAT-5 |
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✓ |
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SCAT-5 follow-up |
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✓ | ✓ | ✓ | ✓ |
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Boxing history |
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✓ | |||
aA: intervention group.
bB: control group.
cSCAT-5: Sport Concussion Assessment Tool-5.