Table 6.
Hazard Ratios of NTG among T2DM with DPP4i and Non-DPP4i User
| Variable | NTG |
Crude |
Adjusted∗ |
||||
|---|---|---|---|---|---|---|---|
| n | PY | IR | HR (95% CI) | P Value | HR (95% CI) | P Value | |
| Non-DPP4i user | 1220 | 1 655 251.00 | 0.74 | 1.00 (reference) | - | 1.00 (reference) | - |
| DPP4i user | 734 | 1 768 746.13 | 0.41 | 0.56 (0.51, 0.61)§ | <0.001 | 0.55 (0.50, 0.62)§ | <0.001 |
CI = confidence interval; DPP4i = dipeptidyl peptidase-4 inhibitor; HR = hazard ratio; IR = incidence rate per 1000 person-years; NTG = normal tension glaucoma; PY = person-years; T2DM = type 2 diabetes mellitus.
∗
Adjusted HR: adjusted by sex, age, region of dwelling, degree of urbanization, insurance premium, comorbidities, CCI score, and medication.
§
P < 0.001.