. 2025 May 19;13(7):e02674-24. doi: 10.1128/spectrum.02674-24

TABLE 2.

The average relative abundance of microbiota at the genus level in the VLS group and control groups^a

	VLS (%）	NV (%）	LA (%)	p1	p2	p3
g__Pseudomonas_E_647464	49.53	52.60	48.85	0.7279	0.7279	0.7279
g__Prevotella	11.98	12.03	20.85	0.6995	0.0837	0.1247
g__Porphyromonas_A_859426	7.09	7.55	1.87	0.6727	0.0585	0.0585
g__Fenollaria	4.96	5.35	6.39	0.6746	0.67471	0.6747
g__Porphyromonas_A_859424	4.38	1.89	2.32	0.2289	0.2394	0.5878
g__Dialister	3.35	3.38	4.57	0.7567	0.4128	0.6264
g__Ezakiella	1.86	1.74	2.24	0.8903	0.8708	0.8708
g__Corynebacterium	1.67	0.57	0.42	0.4356	0.4356	0.4356
g__Peptoniphilus_A	1.51	1.47	1.65	0.6576	0.4173	0.6576
g__Anaerococcus	1.47	1.07	0.90	0.4247	0.0462^b	0.4258
g__Campylobacter_B	1.17	1.00	0.83	0.9034	0.9034	0.9034
g__Methylobacterium	0.90	0.89	0.63	0.6384	0.3306	0.3306
g__Peptoniphilus_B_226777	0.86	0.49	0.74	0.5386	0.9285	0.5386
g__Parvimonas	0.80	0.11	0.08	0.0003^b	0.0003^b	0.7917
g__Peptoniphilus_C	0.69	0.33	0.38	0.1461	0.1461	0.6286
g__Finegoldia	0.55	0.73	0.60	0.5394	0.5394	0.6198
g__Mobiluncus	0.48	0.23	1.35	0.2997	0.2997	0.2997
g__Fusobacterium_C	0.45	0.02	0.14	0.0549	0.1502	0.1502
g__Facklamia_A_322655	0.42	0.19	0.09	0.4996	0.1692	0.4996
g__Negativicoccus	0.31	0.30	0.42	0.8993	0.8993	0.8993
g__W5053	0.29	0.20	0.21	0.9095	0.9095	0.9095
g__Lawsonella	0.29	0.34	0.38	0.7164	0.7164	0.8079
g__Winkia	0.28	0.16	0.05	0.7446	0.6416	0.6416
g__Urinicoccus	0.25	0.19	0.16	0.7350	0.7350	0.7350
g__Varibaculum	0.25	0.15	0.92	0.4975	0.0267^b	0.0267^b
g__Fastidiosipila	0.21	0.04	0.03	0.0210^b	0.0174^b	0.6785
g__Helcococcus	0.20	0.03	0.01	0.1370	0.1370	0.4281
g__Pauljensenia	0.20	0.23	0.09	0.6190	0.2730	0.2934
g__KA00134	0.19	0.17	0.04	0.9762	0.1104	0.2726
g__Peptostreptococcus	0.17	0.03	0.17	0.0666	0.7336	0.0378^b
g__S5.A14a	0.16	0.06	0.18	0.3887	0.7055	0.2682
g__Streptococcus	0.15	0.17	0.10	0.8379	0.8379	0.8379
g__Gleimia	0.12	0.01	0.00	0.2289	0.2289	0.3485
g__Sneathia	0.11	0.03	0.01	0.4500	0.3921	0.4500
g__Staphylococcus	0.10	0.07	0.02	0.7114	0.3318	0.3521
g__UBA1822	0.10	0.10	0.24	0.8450	0.2082	0.2082
Others	2.49	6.09	2.08	NA	NA	NA

^{^a}

VLS, Vulvar lichen sclerosis; NV, Nevus of vulva; LA, Labial adhesions; NA, not applicable. p1, p2, and p3 were the results of Welch's t-test of VLS&NV, VLS&LA, NV&LA, respectively.

^{^b}

Adjusted P < 0.05 with Benjamini-Hochberg correction. Others include the taxa that cannot be classified and taxa with the relative abundance of less than 0.5%.