Fig. 5.

Recurrence of EpCAM mutations in oncogenic driver mutations of colon and Hepatocellular cancers. A EpCAM mutations were analyzed in colon cancer patients using TCGA and cBioPortal datasets. B Patient data from the same datasets were examined for overall survival. The Kaplan–Meier plot shows that patients with EpCAM mutations or alterations have worse survival outcomes compared to those in the unaltered group. C EpCAM mutations were frequently observed alongside driver mutations in genes such as KRAS, BRAF, TP53, and EGFR. D-E EpCAM mutations in hepatocellular cancers demonstrate worst survival