Table 3.
AEs of the studies included in the meta-analysis.
| AE | All grade ES,% (95CI) | I2,100% | Grade≥III ES,% (95CI) | I2,100% |
|---|---|---|---|---|
| Myelosuppression | 32.6 (24.0-41.8) | 50.93 | 17.4 (9.7-26.4) | 54.56 |
| Nausea | 7.3 (3.4-12.1) | 19.62 | NA | NA |
| Vomiting | 11.7 (5.7-19.2) | 47.18 | NA | NA |
| ALT/AST | 11.8 (3.0-24.4) | 80.99 | 1.7 (0.0-8.4) | 45.95 |
| Neurotoxicity | ||||
| Radiculitis | 8.4 (1.5-18.8) | 69.28 | 3.5 (0.0-14.7) | 68.61 |
| Headache | 24.8 (4.6-53.0) | 94.90 | 3.6 (0.0-11.0) | 61.88 |
| Leukoencephalopathy | 6.4 (2.9-10.9) | 0.00 | NA | NA |
NA, Not assessable; ALT, Alanine aminotransferase; AST, Aspartate aminotransferase.