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Immune landscape and survival analysis by TMB and risk groups. (A) Immune cell infiltration scores (e.g., B cells, CD8+ T cells) differ significantly between risk groups (***p < 0.001, **p < 0.01, *p < 0.05). (B) Differential expression of immune-related genes (e.g., ADORA2A, CD27) across risk groups. (C) Kaplan-Meier curves show high TMB + low risk correlates with better survival (p < 0.001). (D) Immune pathway activity (e.g., cytolytic activity, IFN response) varies by risk group.
