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Methyltransferase reactions that result in the formation of N-methylated amides in protein-bound glutamine and asparagine residues. The N-5 and N-4 designations refer to the number of the carboxyl carbon atom that the methyl amine is attached to; heavy lines show the polypeptide backbone. AdoMet, S-adenosyl-l-methionine; AdoHcy, S-adenosyl-l-homocysteine. HemK catalyzes the methylation of RFs; PrmB catalyzes the methylation of the L3 ribosomal protein. See text for references.
