Table 4. Key regulated factor of interleukin in RCC (TRRUST).
| Key TF | Description | Regulated gene | Mode of regulation | p-value | FDR |
|---|---|---|---|---|---|
| HOXA10 | Homeobox A10 | IL11 | Repression | 2.64E − 05 | 1.32E − 04 |
| IL15 | Activation | ||||
| MYB | v-myb myeloblastosis viral oncogene homolog (avian) | IL15 | Activation | 1.67E − 04 | 4.17E − 04 |
| IL7 | Activation | ||||
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | IL1A | Repression | 4.44E − 04 | 5.65E − 04 |
| IL23A | Activation | ||||
| IL4 | Unknown | ||||
| NFKB1 | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | IL1A | Repression | 4.52E − 04 | 5.65E − 04 |
| IL23A | Activation | ||||
| IL4 | Unknown | ||||
| JUN | Jun proto-oncogene | IL1A | Unknown | 0.00267 | 0.00267 |
| IL23A | Unknown |