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. 2025 Jul 1;15:21708. doi: 10.1038/s41598-025-05551-7

Table 2.

Participant characteristics of the FTA and FTC groups.

Variable Category/Group FTA FTC P-value
Age 48.89 ± 12.96 44.77 ± 15.89 0.01
Sex Female 150 (81.97%) 111 (77.08%) 0.34
Male 33 (18.03%) 33 (22.92%)
Diameter < 2 cm 22 (12.02%) 17 (11.81%) 0.55
> 2 cm 34 (18.58%) 26 (18.06%)
> 3 cm 48 (26.23%) 29 (20.14%)
> 4 cm 79 (43.17%) 72 (50.00%)
Composition Cystic 23 (12.57%) 2 (1.39%) 0.00
Solid 159 (86.89%) 141 (97.92%)
Predominantly solid 1 (0.55%) 1 (0.69%)
Margin Regular 171 (93.44%) 61 (42.36%) 0.00
Irregular 12 (6.56%) 83 (57.64%)
Halo Absent 174 (95.08%) 101 (70.14%) 0.00
Irregular halo 9 (4.92%) 43 (29.86%)
Echo Anechoic 3 (1.64%) 0 (0.00%) 0.00
Isoechoic 169 (92.35%) 119 (82.64%)
Very hypoechoic 11 (6.01%) 25 (17.36%)
Texture Even 105 (57.38%) 20 (13.89%) 0.00
Uneven 78 (42.62%) 124 (86.11%)
Internal septations Absent 183 (100.00%) 134 (93.06%) 0.00
Present 0 (0.00%) 10 (6.94%)
Nodule within nodule Absent 183 (100%) 141 (97.92%) 0.17
Present 0 (0.00%) 3 (2.08%)
Calcifications Absent 172 (93.99%) 113 (78.47%) 0.00
Present 11 (6.01%) 31 (21.52%)
ACR-TIRADS ACR-TR1 0 (0.00%) 0 (0.00%)
ACR-TR2 56 (30.60%) 7 (4.86%) 0.00
ACR-TR3 79 (43.17%) 28 (19.44%)
ACR-TR4 48 (26.23%) 109 (75.7%)
ACR-TR5 0 (0.00%) O (0.00%)
C-TIRADS C-TR2 0 (0.00%) 0 (0.00%)
C-TR3 182 (99.45%) 132 (91.67%) 0.00
C-TR4A 1 (0.55%) 12 (8.33%)
C-TR4B to 5 0 (0.00%) 0 (0.00%)

TI-RADS, Thyroid Imaging Reporting and Data System; ACR, American College of.

TI-RADS, Thyroid Imaging Reporting and Data System; ACR, American College of Radiology; C–TI-RADS, Chinese TI-RADS; SD, standard deviation; FTA, follicular thyroid adenoma; FTC, follicular thyroid cancer.