Fig. 5.

Genes regulating Bmp signaling are downregulated in Lgr6-null osteoblasts cultures derived from mice: (A) Enrichment plot. (B) Heat map comparing Lgr6null and control. (C) RT-qPCR analysis confirmed decreased expression of genes in the Bmp pathway in Lgr6-null samples. N = 4 male-mice/genotype. Data analyzed by Student’s t-tests *p < 0.05; **p < 0.001 ***p < 0.001; ****p < 0.0001 vs control.