Fig. 8.

Lgr6 and Bmp2 expression is enriched in periosteal-derived SSPC clusters. (A) Integrated data sets of scRNA-seq of fractured and intact periosteal cells were visualized using UMAP-based clustering, and 13 distinct cell clusters (Cluster 0–12) were identified. (B) The integrated dataset contained hematopoietic CD45+ (Ptprc) and mesenchymal (Prrx1+) cells. (C) UMAPs showing indicated gene expression in periosteal cells derived from uninjured (intact) and injured (fractured) bones.