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. 2025 Jul 1;15:20884. doi: 10.1038/s41598-025-05646-1

Table 9.

Single dose Pharmacokinetic profile of atorvastatin, LIPITOR and solidified SNEDDS (mean ± SD, n = 3).

Treatment groups AUC0 − t (ng/ml*h) Cmax (ng/ml) Tmax (h) t1/2 (h) MRT (h) Ke (h− 1)
Atorvastatin 136.13 ± 16.75 11.738 ± 2.241 4 ± 0.00 7.278 ± 1.859 8.735 ± 0.824 0.095 ± 0.003
LIPITOR 220.06 ± 15.60 28.903 ± 3.187 2 ± 0.00 6.051 ± 1.873 7.272 ± 0.984 0.114 ± 0.001
Solidified SNEDDS (SF10) 305.98 ± 26.05 53.146 ± 5.707 2 ± 0.00 6.148 ± 2.628 6.339 ± 0.641 0.112 ± 0.002

MRT: mean residence time. AUC0−t: area under the plasma concentration−time plot from 0 h to time. Ke(h−1): elimination rate constant. t1/2: elimination half−life. Cmax: peak plasma drug concentration. Tmax: time at which Cmax was observed.