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. 2025 Jul 1;11:192. doi: 10.1038/s41531-025-01043-7

Table 2.

Brain regions with differences in magnetic susceptibility values among groups

Regions MNI coordinate cluster size pFWE-corr-value peak t value
X Y Z
QSM
PD-RBD+> PD-RBD-
left rectus gyrus 0 31 −25 62 0.042 5.17
PD-RBD+ <PD-RBD-
right superior frontal gyrus, dorsolateral 15 18 30 224 <0.001 −4.57
PD-RBD+> HC
left SNpc −10 −22 −18 108 0.001 5.83
right SNpc 11 −21 −16 140 <0.001 6.42
right precentral gyrus 52 −1 34 66 0.028 5.56
left middle cingulate cortex −12 −24 50 95 0.002 4.68
right precentral gyrus 15 −23 66 69 0.021 4.14
PD-RBD+ <HC
right postcentral gyrus 13 −34 67 73 0.014 −4.72
PD-RBD- <HC
left inferior cerebellum −1 −55 −41 86 0.004 −4.63
χpara
PD-RBD+ <PD-RBD-
left middle temporal gyrus −48 −33 −15 69 0.018 −4.39
PD-RBD+> HC
left SNpc −10 −22 −18 120 <0.001 5.66
right SNpc 11 −21 −15 163 <0.001 6.94
PD-RBD-> HC
left inferior temporal gyrus −45 −27 −23 140 <0.001 4.44
left middle temporal gyrus −53 −32 −15 61 0.041 4.08
PD-RBD- <HC
left cerebellar lobule IX −2 −55 −41 79 0.007 −4.79

MNI Montreal Neurological Institute, pFWE-corr-value the p-value of familywise error correction, QSM quantitative susceptibility mapping, χpara paramagnetic susceptibility mapping, PD-RBD+ Parkinson’s disease with secondary rapid eye movement sleep behavior disorder, PD-RBD- Parkinson’s disease without rapid eye movement sleep behavior disorder, SNpc substantia nigra pars compacta.