Table 2.
Comparison of coronary computed tomography angiographic findings according to the tertiles of serum lipoprotein(a).
| Characteristics | Non-DM | DM | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Overall (n = 6,252) | Tertile 1 ≤ 5.6 mg/dl (n = 2,071) | Tertile 2 5.7 ~ 15.0 mg/dl (n = 2,101) | Tertile 3 ≥ 15.1 mg/dl (n = 2,080) | p-valuea | Overall (n = 949) | Tertile 1 ≤ 4.8 mg/dl (n = 317) | Tertile 2 4.9 ~ 13.4 mg/dl (n = 317) | Tertile 3 ≥ 13.5 mg/dl (n = 315) | p-valuea | |
| Mean CACS | 33.4 ± 136.8 | 33.7 ± 127.7 | 31.8 ± 139.7 | 34.9 ± 142.7 | 0.756 | 99.2 ± 284.4 | 100.2 ± 297.2 | 80.3 ± 262.2 | 117.3 ± 292.1 | 0.261 |
| CACS, no. (%) | 0.297 | 0.417 | ||||||||
| 0 | 4,309 (68.9) | 1,456 (70.3) | 1,442 (68.6) | 1,411 (67.8) | 439 (46.3) | 151 (47.6) | 155 (48.9) | 133 (42.2) | ||
| 1–10 | 603 (9.6) | 180 (8.7) | 218 (10.4) | 205 (9.9) | 94 (9.9) | 30 (9.5) | 30 (9.5) | 34 (10.8) | ||
| 11–100 | 847 (13.5) | 278 (13.4) | 287 (13.7) | 282 (13.6) | 216 (22.8) | 70 (22.1) | 78 (24.6) | 68 (21.6) | ||
| 101–400 | 366 (5.9) | 114 (5.5) | 110 (5.2) | 142 (6.8) | 140 (14.8) | 47 (14.8) | 37 (11.7) | 56 (17.8) | ||
| > 400 | 127 (2.0) | 43 (2.1) | 44 (2.1) | 40 (1.9) | 60 (6.3) | 19 (6.0) | 17 (5.4) | 24 (7.6) | ||
| Any coronary plaque, no. (%) | 2,026 (32.4) | 637 (30.8) | 688 (32.7) | 701 (33.7) | 0.118 | 531 (56.0) | 175 (55.2) | 171 (53.9) | 185 (58.7) | 0.454 |
| Plaque characteristics, no. (%) | ||||||||||
| Calcified plaque | 1,912 (30.6) | 601 (29.0) | 653 (31.1) | 658 (31.6) | 0.156 | 499 (52.6) | 162 (51.1) | 160 (50.5) | 177 (56.2) | 0.288 |
| Mixed plaque | 166 (2.7) | 55 (2.7) | 47 (2.2) | 64 (3.1) | 0.240 | 83 (8.7) | 27 (8.5) | 23 (7.3) | 33 (10.5) | 0.353 |
| Non-calcified plaque | 275 (4.4) | 79 (3.8) | 88 (4.2) | 108 (5.2) | 0.081 | 88 (9.3) | 23 (7.3) | 32 (10.1) | 33 (10.5) | 0.312 |
| Obstructive coronary artery disease , no. (%) | 318 (5.1) | 93 (4.5) | 106 (5.0) | 119 (5.7) | 0.195 | 124 (13.1) | 32 (10.1) | 39 (12.3) | 53 (16.8) | 0.038 |
Values are shown as mean ± standard deviation or number (%).
aP-value is based on the comparison of the three groups.
CACS = coronary artery calcium score; DM = diabetes mellitus.