Table 3.
Association between serum lipoprotein(a) levels and coronary computed tomography angiographic findings accoding to the presence of diabetes mellitus.
| Variables | Non-DM | DM | ||||||
|---|---|---|---|---|---|---|---|---|
| Univariable | Multivariable | Univariable | Multivariable | |||||
| Odds ratio (95% CI) | p-value | Odds ratio (95% CI) | p-value | Odds ratio (95% CI) | p-value | Odds ratio (95% CI) | p-value | |
| Any coronary plaque | ||||||||
| Tertile 1 (reference) | 1 | 1 | 1 | 1 | ||||
| Tertile 2 | 1.096 (0.962–1.249) | 0.168 | 1.076 (0.929–1.245) | 0.328 | 0.950 (0.695–1.299) | 0.750 | 0.912 (0.651–1.277) | 0.593 |
| Tertile 3 | 1.144 (1.005–1.304) | 0.043 | 1.153 (0.995–1.336) | 0.058 | 1.155 (0.843–1.583) | 0.371 | 1.058 (0.752–1.489) | 0.745 |
| Calcified plaque | ||||||||
| Tertile 1 (reference) | 1 | 1 | 1 | 1 | ||||
| Tertile 2 | 1.103 (0.966–1.259) | 0.147 | 1.083 (0.934–1.256) | 0.289 | 0.975 (0.714–1.331) | 0.874 | 0.930 (0.664–1.303) | 0.675 |
| Tertile 3 | 1.132 (0.991–1.292) | 0.067 | 1.134 (0.977–1.316) | 0.098 | 1.227 (0.897–1.678) | 0.200 | 1.117 (0.794–1.572) | 0.525 |
| Mixed plaque | ||||||||
| Tertile 1 (reference) | 1 | 1 | 1 | 1 | ||||
| Tertile 2 | 0.839 (0.566–1.244) | 0.382 | 0.872 (0.580–1.310) | 0.509 | 0.840 (0.471–1.500) | 0.556 | 0.909 (0.500–1.651) | 0.754 |
| Tertile 3 | 1.164 (0.807–1.677) | 0.417 | 1.227 (0.835–1.804) | 0.298 | 1.257 (0.737–2.145) | 0.402 | 1.552 (0.888–2.714) | 0.123 |
| Non-calcified plaque | ||||||||
| Tertile 1 (reference) | 1 | 1 | 1 | 1 | ||||
| Tertile 2 | 1.102 (0.808–1.503) | 0.538 | 1.048 (0.764–1.439) | 0.771 | 1.435 (0.820–2.513) | 0.206 | 1.495 (0.845–2.645) | 0.168 |
| Tertile 3 | 1.381 (1.026–1.858) | 0.033 | 1.348 (0.993–1.830) | 0.056 | 1.496 (0.857–2.611) | 0.156 | 1.735 (0.980–3.072) | 0.059 |
| Obstructive coronary artery disease | ||||||||
| Tertile 1 (reference) | 1 | 1 | 1 | 1 | ||||
| Tertile 2 | 1.130 (0.850–1.503) | 0.401 | 1.098 (0.815–1.480) | 0.537 | 1.249 (0.761–2.051) | 0.379 | 1.360 (0.811–2.283) | 0.244 |
| Tertile 3 | 1.291 (0.977–1.705) | 0.072 | 1.254 (0.934–1.682) | 0.132 | 1.802 (1.126–2.882) | 0.014 | 2.051 (1.248–3.372) | 0.005 |
CI = confidence interval; DM = diabetes mellitus.
Covariates in the multivariable model include age, sex, obesity, hypertension, current smoking, family history of coronary artery disease, creatinine, corrected low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol.