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. 2005 Sep 15;19(18):2224–2235. doi: 10.1101/gad.1338905

Figure 1.

Figure 1.

Tn10 and conformational changes in the Tn10 transpososome. (A) The structure of Tn10. The outside end (OE) contains the terminal-binding site (T) and subterminal-binding site (ST) for transposase and an IHF-binding site. The inside end (I) does not contain an IHF site. Half arrows are the terminal inverted repeats. Proteins encoded by Tn10 are indicated. (B) The Tn10 transpososome is shown to undergo several structural changes (see text) over the course of the transposition reaction. (Solid line with arrow) Duplex OE DNA; (dashed line) flanking donor DNA; (filled circle) IHF; (oval) transposase; (TCC) target capture complex.