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. 2025 Jul 1;26:335. doi: 10.1186/s12882-025-04265-2

Table 1.

Tubule injury score

Grade Injury Pathology description
0 None Normal tubule
1 Slight Mild blebbing, loss of brush
2 Mild Intensive blebbing, mild vacuolization
3 Moderate Shrunken nuclei, intensive vacuolization
4 Severe

Necrotic/apoptotic cells

Basement membrane denudation/rupture

5 Necrosis Total tubule necrosis