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Relationship between MIC values and specific carbapenemases
| Antibiotic | MIC Range (µg/mL) | MIC ≥ 16 µg/mL (%) |
blaKPC−2 (n = 42) |
blaNDM−5 (n = 18) |
blaOXA−48 (n = 8) |
p-value |
|---|---|---|---|---|---|---|
| Imipenema | 8-≥ 16 | 97.1% | 97.6% ≥ 16 | 94.4% ≥ 16 | 87.5% ≥ 16 | 0.21 |
| Meropenema | 8-≥ 16 | 97.1% | 100% ≥ 16 | 100% ≥ 16 | 100% ≥ 16 | / |
aActual MIC of most strains exceeds detection limit (16 μg/mL)
