Table 2.
Visual Acuity and Refraction, Keratometry and Pachymetry, and Corneal Biomechanical Parameters Before and After Accelerated-Collagen Crosslinking (N:70)
| Baseline | 1 Month | 6 Months | 12 Months | P* | |
|---|---|---|---|---|---|
| Mean ± SD | |||||
| Visual Acuity and Refraction | |||||
| UCVA, logMAR | 0.80 ± 0.39 | 0.82 ± 0.36 | 0.77 ± 0.30 | 0.83 ± 0.36 | 0.182 |
| BCVA, logMAR | 0.51 ± 0.32 | 0.44 ± 0.20 | 0.39 ± 0.19 | 0.41 ± 0.19 | 0.396 |
| Sphere | −5.03 ± 5.45 | −4.47 ± 4.97 | −4.74 ± 5.07 | −5.83 ± 4.83 | 0.219 |
| Cylinder | −4.26 ± 2.80 | −5.50 ± 3.24 | −5.01 ± 3.15 | −5.28 ± 2.70 | 0.647 |
| MRSE | −6.79 ± 6.12 | −6.95 ± 5.42 | −7.55 ± 5.87 | −8.45 ± 5.13 | 0.261 |
| Keratometry and Pachymetry | |||||
| K1 | 51.63 ± 8.62 | 52.82 ± 8.28 | 52.05 ± 9.26 | 51.23 ± 5.79 | 0.054 |
| K2 | 56.40 ± 8.19 | 58.20 ± 8.70 | 57.44 ± 8.35 | 56.22 ± 5.87 | 0.054 |
| Kmean | 53.84 ± 8.41 | 55.33 ± 8.40 | 54.46 ± 8.95 | 53.59 ± 5.75 | 0.012 |
| Kmax | 65.51 ± 10.27 | 67.73 ± 11.38 | 64.92 ± 10.29 | 65.19 ± 7.43 | 0.186 |
| CCT Pupil Center | 467.15 ± 50.75 | 452.92 ± 49.77 | 461.45 ± 55.30 | 459.48 ± 53.99 | 0.015 |
| CCT Vertex Normal | 445.71 ± 57.41 | 425.25 ± 59.22 | 441.81 ± 59.57 | 435.76 ± 59.89 | 0.002 |
| CCT Thinnest Location | 431.35 ± 58.93 | 413.15 ± 61.06 | 415.84 ± 75.60 | 422.52 ± 62.46 | 0.006 |
| Corneal Biomechanics | |||||
| DAR | 6.64 ± 2.30 | 6.61 ± 2.15 | 6.24 ± 1.70 | 6.45 ± 1.19 | 0.098 |
| IR | 13.78 ± 3.93 | 13.70 ± 3.70 | 12.99 ± 4.56 | 13.60 ± 2.82 | 0.145 |
| ARTh | 206.52 ± 111.85 | 193.78 ± 118.11 | 165.83 ± 100.04 | 186.40 ± 106.73 | 0.457 |
| SPA 1 | 53.24 ± 22.03 | 47.05 ± 19.85 | 48.55 ± 19.94 | 51.12 ± 20.68 | 0.373 |
| SSI | 0.74 ± 0.26 | 0.73 ± 0.25 | 0.70 ± 0.25 | 0.66 ± 0.14 | 0.723 |
| BAD D | 13.87 ± 7.28 | 15.27 ± 6.73 | 15.01 ± 6.37 | 14.41 ± 6.05 | 0.659 |
*Statistical analysis used: §–Friedman Test.; UCVA-Uncorrected Visual Acuity; BCVA-Best Corrected Visual Acuity; MRSE-Manifest Refraction Spherical Equivalent;; K1-Flat Keratometry; K2-Steep Keratometry; Kmean-Mean Keratometry; Kmax-Maximal Keratometry; CCT-Central Corneal Thickness; DAR- Deformation Amplitude Ratio; IR- Integrated Radius; ARTh-Ambrósio relational thickness to the horizontal profile; SPA 1 Stiffness Parameter at first applanation; SSI- Stress Strain Index; BAD D-Belin/Ambrósio Enhanced Ectasia Total Deviation Display