Figure 1.

Eosinophil accumulation after saline or OA challenge in sham or sensitized mice. Eosinophil accumulation in BAL (a) and lung tissue (b) at 6 and 24 h after saline or OA challenge in CCR3-deficient (solid bars) or wild-type littermate (open bars) mice. Significant differences between wild-type control and CCR3−/− mice are indicated as *, P < 0.04 and **, P < 0.001, as determined by unpaired Student's t test. Results are presented as mean ± SEM (n = 11–19 mice/group). Eosinophil accumulation in blood (c) and spleen (d) at 6 and 24 h after saline or OA challenge in CCR3-deficient (solid bars) or wild-type littermate (open bars) mice. Results are presented as mean ± SEM (n = 6–7 mice/group); **, P < 0.001.