Table 2.
Mast cell localization within murine trachea (mean/10hpf)
Submucosal | Intraepithelial | |
---|---|---|
Sham wild type | 0.60 ± 0.10 | 0 |
Sham CCR3−/− | 0.95 ± 0.12 | 0.17 ± 0.08 |
OA wild type | 0.60 ± 0.06 | 0.19 ± 0.05 |
OA CCR3−/− | 0.80 ± 0.10 | 1.00 ± 0.20* |
Results shown are expressed as the means ± SEM (sham-treated mice, n = 4; OA-challenged mice, n = 7). The significant difference between OA-challenged wild-type and OA-challenged CCR3−/− mice is indicated as
, P < 0.002, as determined by unpaired Student's t test.