Skip to main content
. 2002 Jan 29;99(3):1610–1615. doi: 10.1073/pnas.032670899

Figure 1.

Figure 1

MRI data reveal significantly larger lesions in APP751-overexpressing mice than in their WT littermates at 24 h after the MCA occlusion. (a) Typical examples of ischemic lesions in 8-month-old WT and APP751 TG mice. (b) At 8 months of age, both TG pedigrees develop 34% larger infarcts than WT mice (**, P < 0.01 from F10 and F15, ANOVA). (c) At 20 months, the infarcts are 35% larger in F10 pedigree and 41% larger in F15 pedigree than in WT littermates (****, P < 0.0001 from F10 and F15, ANOVA). n = 6–8 mice per group at both ages.