Figure 2.

(A) Confocal image of phalloidin-labeled striatal neurons in primary culture. Spines, one of which is indicated by an arrow, were defined as small actin rich protrusions. (B) Percentage of spines exhibiting D1 receptor immunosignal in neurons 15 min after exposure to vehicle or NMDA (0.5 mM) for 30 s. Data represent mean values from two independent observers and five experiments; bars indicate SEM. *, P < 0.001. In total, 158 spines were examined.