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. 2025 Jul 4;26:217. doi: 10.1186/s12875-025-02911-0

Table 3.

Initial symptoms observed by the patient

Breakdown of 1 st symptoms observed by the patient (n = 51) n (%)
Mobility disorders 45 88
 Trembling 32 71
 Slowness of movement 24 53
 Morning stiffness 18 40
 Reduced movement 13 29
 Loss of balance 10 22
 Feeling of sticky feet 7 16
 Mobility disorders 6 13
 Mood changes 23 45
 Mood changes during the day, feelings of anxiety/anxiety/panic 13 57
 Feelings of depression 12 52
 Apathy 10 43
 Loss of interest 9 39
Memory and attention disorders 12 24
 Difficulty concentrating 8 67
 Forgetting recent events 7 58
 Loss of the thread of conversation 3 25
 Difficulty remembering names/numbers/events. 2 17
Sleep disorders 10 20
 Frequent waking at night 7 70
 Difficulty falling asleep 6 60
 Difficulty getting back to sleep 5 50
 Incessant need to move your legs 3 30
 Early morning awakening 2 20
 Sleep disturbed by changes in position 2 20
Painful symptoms 9 18
 Cervical/lumbar pain 6 67
 Painful stiffness during the day or in the hand 5 56
 Painful contractions on waking 2 22
 Burning/tingling/squeezing pain 2 22
Digestive symptoms 8 16
 Constipation 7 88
 Stomachache 1 13
 Excess saliva 1 13
Other symptoms 6 12
 Taste and smell disorders 2 33
 Unexplained fatigue during the day 2 33
 Dizziness/head spinning on lifting 1 17
 Loss of self-esteem 1 17
Bladder and sexual function disorders 5 10
 Altered libido 3 60
 Difficulty having sexual intercourse 3 60
 Urgent need to urinate 2 40
 Gets up at night to urinate 2 40