Figure 2.

Structural characterization of retrocyclin. (a) CD spectrum demonstrating the similarity in structure between retrocyclin and RTD-1, both at 0.5 mg/ml in a 1:1 mixture of trifluoroethanol in PBS at pH 7.4. (b) A hypothetical model of retrocyclin made by templating its sequence on the backbone of a similar peptide from porcine neutrophils, protegrin-1 (PDB accession code: 1PG1). (c) A cartoon version of b, wherein arginines are black, cysteines are gray, and the other residues are identified by single letter code. (d) A similar cartoon of rhesus RTD-1, indicating the similarity in structure with retrocyclin.