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. 2025 Jul 4;25:269. doi: 10.1186/s12880-025-01820-z

Table 1.

ACR TI-RADS and revised thyroid nodule size criteria

Category ACR TI-RADS Strategy 1 [9] Strategy 2 [10]
TR1 (benign) No FNAB No FNAB

> 4.0 cm: FNAB

1.0–4.0 cm: Follow-up

TR2 (not suspicious) No FNAB No FNAB

> 4.0 cm: FNAB

1.0–4.0 cm: Follow-up

TR3 (mildly suspicious)

≥ 2.5 cm: FNAB

≥ 1.5 cm: Follow-up

≥ 1.5 cm: FNAB

≥ 1.5 cm: FNAB

1.0–1.5 cm: Follow-up

TR4 (moderately suspicious)

≥ 1.5 cm: FNAB

≥ 1.0 cm: Follow-up

≥ 1.0 cm: FNAB

≥ 1.0 cm: FNAB

≥ 0.5 cm Follow-up

TR5 (highly suspicious)

≥ 1.0 cm: FNAB

≥ 0.5 cm: Follow-up

≥ 1.0 cm: FNAB

≥ 0.5 cm: Follow-up

≥ 1.0 cm: FNAB

0.5–0.9 cm: Consider FNAB

≥ 0.5 cm Follow-up

Abbreviations: ACR, American College of Radiology; FNAB, fine needle aspiration biopsy; TI-RADS, Thyroid Imaging Reporting and Data System