Table 3. Change in haemoglobin (baseline vs 4 months) and MLHFQ at 4 months according to quarters of age.

	Age groups (years)												P interaction
	<67(n=284)			≥67–≤73(n=284)			>73–≤79(n=283)			>79(n=285)
	FDI(n=146)	UC(n=138)	Treatment effect(95% CI, p value)	FDI(n=142)	UC(n=142)	Treatment effect(95% CI, p value)	FDI(n=128)	UC(n=155)	Treatment effect(95% CI, p value)	FDI(n=153)	UC(n=132)	Treatment effect(95% CI, p value)
Haemoglobin (g/dL)
BL	12.1(1.2)	12.0(1.2)		12.1(1.1)	12.0(1.2)		12.0(1.1)	12.0(1.2)		11.8(1.1)	11.9(1.0)
4 m	13.0(1.4)N=113	12.1(1.6)N=113		12.9(1.3)N=109	12.4(1.4)N=114		12.9(1.3)N=101	12.3(1.4)N=110		12.5(1.4)N=127	12.0(1.3)N=101
Δ (BL vs 4 m)	0.8(1.5)N=113	0.1(1.1)N=113	0.7(0.4, 1.1)<0.001	0.7(1.4)N=109	0.4(1.2)N=114	0.3(−0.2, 0.7)0.07	1.0(1.3)N=101	0.2(1.3)N=110	0.8(0.5, 1.2)<0.001	0.7(1.2)N=127	0.0(1.2)N=101	0.7(0.4, 1.0)<0.001	0.17
MLHFQ (4 m)
Overall (4 m)	49(30)N=122	47(27)N=112	2(−6, 9)0.70	36(28)N=128	39(27)N=127	−3(−10, 4)0.35	32(25)N=114	40(26)N=127	−8(−15, –2)0.014	32(24)N=138	36(25)N=118	−4(−10, 2)0.21	0.26
Physical (4 m)	22(12)N=121	21(12)N=112	1(−3, 4)0.78	18(12)N=128	20(12)N=127	–3(−6, 0)0.094	16(11)N=112	20(11)N=127	–4(−7, –1)0.007	17(11)N=138	19(11)N=117	–2(−5, 1)0.14	0.23
Emotional (4 m)	12(9)N=122	12(8)N=113	0(−2, 2)0.95	8(8)N=128	9(8)N=127	0(−2, 2)0.90	7(7)N=114	8(7)N=127	–2(−4, 0)0.086	7(7)N=138	7(7)N=117	–1(−2, 1)0.61	0.64

BL, baseline; FDI, intravenous ferric derisomaltose; m, month; MLHFQ, Minnesota Living with Heart Failure Questionnaire; UC, usual care.