Figure 3.

Reduced response of msh-2 mutant worms to DNA damage-induced apoptosis in the germ line. Twenty-four hours after the L4/adult molt, wild-type (▪) and msh-2 (▴) mutant worms were either irradiated (b and c) or left unirradiated (a). Worms were mounted for microscopy at time intervals of 3 h and examined for the number of apoptotic cell corpses in one arm of the gonad. Fifteen worms of each genotype were used in these experiments. For those time points indicated with arrows, there is a significant difference (P < 0.05 by Mann–Whitney nonparametric test) in the number of corpses.