Table 1.

Study characteristics

Included Article Characteristics (N = 44)	n	%	References
Intervention location type
Academic medical center(s)	24	54.5	19–42
Community clinic(s)	6	13.6	43–48
Health system clinic(s)	5	11.4	49–53
Public health/safety-net clinic(s)	2	4.5	54,55
More than one type of location	3	6.8	56–58
Not clinic based	4	9.1	59–62
Year of publication
2000–2005	5	11.4	27,31,41,51,56
2006–2010	6	13.6	28,33,59–62
2011–2015	11	25.0	19,21,24,26,32,34,39,45,52,53,57
2016–2020	22	50.0	20,22,23,25,29,30,35–38,40,42–44,46–50,54,55,58
Study funding source
Governmental agency	12	27.3	19,26–28,31,32,40,45,46,50,52,61
Other funding (eg, foundation, institutional)	4	9.1	30,37,60,62
For-profit organization/company	2	4.5	25,44
More than one type of funding	15	34.1	20–22,24,34,35,41,42,48,51,53–55,57,58
No funding	11	25.0	23,29,33,36,38,39,43,47,49,56,59
Study design
Cohort study	33	75	19,20,22–26,29,30,32,36–39,41–49,51–56,59–62
Randomized controlled trial	11	25	21,27,28,31,33–35,40,50,57,58
Comparison or control group
Present	30	68.2	19,21,22,24,26–29,31–38,40,41,43–45,47,48,50,51,54,56–59
Absent	14	31.8	20,23,25,30,39,42,46,49,52,53,55,60–62
Study interventions’ use of GC intervention domains
Risk content and communication included	9	20.5	27,30,42–44,46,48,52,55
Educational content includeda	22	50.0	20,24,27,31,37,38,40–42,44,46–49,51,52,54,56,59–62
Psychotherapeutic content includedb	15	34.1	20,21,25,28,31,34–36,41,43,44,49,54,57,58

GC, genetic counseling.

^aIncludes education interventions targeting providers and patients.

^bIncludes studies that had GC as a component of the intervention. Although GC typically includes risk communication and education, if not explicitly included as a discrete components of study interventions, GC was not counted in the risk and educational domains.