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. 2025 Jun 25;17:1546977. doi: 10.3389/fnagi.2025.1546977

Table 1.

Characteristics of participants.

Variables AD (n = 42) HC (n = 49) F (χ2) p
Sex (male), n (%) 21(50.0) 27 (55.1) 0.236 0.63
Age, years, Mean ± SD 74.14 ± 5.44 72.67 ± 6.82 1.26 0.27
Education level, Mean ± SD 7.00 ± 2.26 6.61 ± 2.34 0.64 0.42
MMSE, scores, Mean ± SD 17.55 ± 2.46 27.51 ± 1.23 623.03 <0.01
MoCA, scores, Mean ± SD 14.05 ± 2.55 26.65 ± 0.88 1055.50 <0.01
AVLT-H-SR, scores, Mean ± SD 6.02 ± 0.78 8.82 ± 1.51 116.85 <0.01
AVLT-H-LR, scores, Mean ± SD 4.12 ± 0.86 6.94 ± 1.33 138.89 <0.01
BNT, scores, Mean ± SD 21. 29 ± 5.55 28.94 ± 1.18 88.81 <0.01
TMT-B time, seconds, Mean ± SD 239.12 ± 47.28 70.84 ± 34.42 383.82 <0.01
CDT, scores, Mean ± SD 1.64 ± 0.69 3.79 ± 0.41 330.26 <0.01
CDR-SB, scores, Mean ± SD 2.85 ± 1.50 0.20 ± 0.25 147.48 <0.01
HAMD, scores, Mean ± SD 2.95 ± 1.45 2.12 ± 1.725 2.18 0.14
HAMA, scores, Mean ± SD 3.31 ± 1.63 3.08 ± 1.43 0.51 0.48
ADCS-ADL, scores, Mean ± SD 5.24 ± 2.61 0.59 ± 0.64 145.10 <0.01

AD, Alzheimer’s disease; HC, healthy controls; SD, standard deviation; MMSE, Mini-Mental State Examination; MOCA, Montreal Cognitive Assessment; AVLT-H-SR, short-term delayed recall of auditory verbal learning test-Huashan version; AVLT-H-LR, long-term delayed recall of auditory verbal learning test-Huashan version; TMT-B, Trail Making Test-B; BNT, Boston naming test; CDT, clock drawing test; CDR-SB, Clinical Dementia Rating Scale-Sum of Boxes; HAMD, Hamilton Depression Scale; HAMA, Hamilton Anxiety Scale; ADCS-ADL, Alzheimer’s Disease Collaborative Study - Daily Living Ability Scale.