Table 2.
Brain regions with reduced cortical thickness in the AD-HC groups.
| Cluster | Hemisphere | T-value | Size | Peak MNI coordinate | Mean CT in AD group (mm) | Mean CT in HC group (mm) | Overlap of atlas | Region |
|---|---|---|---|---|---|---|---|---|
| Cluster 1 | L | 4.6 | 472 | −46, −26, 7 | 2.23 ± 0.14 | 2.39 ± 0.15 | ||
| 38% | Left transverse temporal | |||||||
| 49% | Left superior temporal | |||||||
| 12% | Left supramarginal | |||||||
| 1% | Left insula | |||||||
| Cluster 2 | R | 5.0 | 1,365 | 41, −22, 6 | 2.77 ± 0.23 | 3.01 ± 0.17 | ||
| 39% | Right superior temporal | |||||||
| 12% | Right temporal pole | |||||||
| 8% | Right entorhinal | |||||||
| 10% | Right transverse temporal | |||||||
| 14% | Right insula | |||||||
| 9% | Right supramarginal | |||||||
| 5% | Right fusiform |
AD, Alzheimer’s disease; HC, Health control; CT, Cortical thickness.