Table 3.
Brain regions with GMV loss in the AD-HC groups.
| Cluster | T-value | Size | Peak MNI coordinate | Overlap of atlas | Region |
|---|---|---|---|---|---|
| Cluster 1 | 7.2 | 4,221 | 21, −33, 2 | ||
| 16% | Right hippocampus | ||||
| 8% | Right parahippocampal | ||||
| 12% | Right fusiform | ||||
| 17% | Right posterior temporal lobe | ||||
| 9% | Right amygdala | ||||
| 6% | Right thalamus | ||||
| 11% | Right inferior temporal | ||||
| 7% | Right limbic lobe | ||||
| 5% | Middle temporal gyrus | ||||
| Cluster 2 | 6.5 | 2,231 | −46.5, −53, −27 | ||
| 7% | Left hippocampus | ||||
| 7% | Left parahippocampal | ||||
| 16% | Left fusiform | ||||
| 8% | Left amygdala | ||||
| 37% | Left posterior temporal lobe | ||||
| 8% | Left inferior temporal | ||||
| 9% | Left thalamus |
GMV, Gray matter volume; AD, Alzheimer’s disease; HC, Health control; MNI: Montreal Neurological Institute.