Table 1:
Anesthetic considerations of sedatives for outpatient interventional radiology procedures [38, 43–45]
| Characteristic | Dexmedetomidine | Ketamine | Midazolam | Propofol | Remimazolam |
|---|---|---|---|---|---|
| Low cardiac depression risk | ✔ | ✔ | ✔ | ||
| Low respiratory depression risk | ✔ | ✔ | ✔ | ✔ | |
| Rapid onset of action | ✔ | ✔ | ✔ | ||
| Rapid postoperative recovery | ✔ | ✔ | |||
| Reversal agent available | ✔ | ✔ | |||
| Analgesic effect | ✔ | ✔ | |||
| Anxiolytic effect | ✔ | ✔ | ✔ | At low doses | ✔ |
| Active metabolite | ✔ | ✔ | |||
| Metabolism | Hepatic | Hepatic | Hepatic | Hepatic & extrahepatic |
Tissue esterases |
| Ready to use | Dilution | ✔ | ✔ | ✔ | Reconstitution |