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Pyruvate cycling in two highly responsive (832/13 and 834/40) and two poorly responsive (832/2 and 832/1) INS-1-derived β cells
| Experimental condition | Pyruvate cycling (relative to TCA cycle
flux = 1)
|
|||
|---|---|---|---|---|
| 832/13 (n = 4) | 834/40 (n = 3) | 832/1 (n = 2) | 832/2 (n = 4) | |
| 3 mM glucose | 0.30 ± 0.06 | 0.36 ± 0.08 | 0.50 ± 0.08 | 0.38 ± 0.07 |
| 6 mM glucose | 0.65 ± 0.03 | — | — | 0.50 ± 0.05 |
| 12 mM glucose | 1.07 ± 0.03 | 0.89 ± 0.08 | 0.55 ± 0.06 | 0.77 ± 0.09 |
