Table 1.
RNAs of cellular genes upregulated 4-fold or higher by the IE86 protein
| GenBank accession nos. | Description |
|---|---|
| DNA replication | |
| M87338 | Human replication factor C, 40-kDa subunit (A1) mRNA |
| M87339 | Human replication factor C, 37-kDa subunit mRNA |
| M63488 | Human replication protein A, 70-kDa subunit mRNA |
| J05614 | Human proliferating cell nuclear antigen (PCNA) gene, promoter region |
| M97856 | Homo sapiens histone-binding protein mRNA |
| U81375 | Human placental equilibrative nucleoside transporter 1 (hENT1) mRNA |
| X59543 | Human mRNA for M1 subunit of ribonucleotide reductase |
| X02308 | Human mRNA for thymidylate synthase (EC 2.1.1.45) |
| J00140 | Human dihydrofolate reductase gene |
| L07541 | Human replication factor C, 38-kDa subunit mRNA |
| D84557 | H. sapiens mRNA for HsMCM6 |
| D38073 | Human mRNA for hRlf beta subunit (p102 protein) (MCM3) |
| X14850 | Human H2A.X mRNA encoding histone H2A.X |
| X00737 | Human mRNA for purine nucleoside phosphorylase (PNP; EC 2.4.2.1) |
| X06745 | Human mRNA for DNA polymerase alpha subunit |
| M15205 | Human thymidine kinase gene with clustered Alu repeats in introns |
| D55716 | Human mRNA for P1cdc47 (MCM7) |
| X74795 | H. sapiens P1-Cdc46 mRNA (MCM5) |
| J03626 | Human UMP synthase mRNA |
| Cell cycle/proliferation | |
| U65410 | Human Mad2 (hsMAD2) mRNA |
| X05360 | Human CDC2 gene involved in cell cycle control |
| X13293 | Human mRNA for B-myb gene |
| M15796 | Human cyclin protein gene, complete cds |
| M73812 | Human cyclin E mRNA sequence |
| M96577 | H. sapiens (E2F-1) pRB-binding protein mRNA |
| U18271 | Human thymopoietin (TMPO) gene |
| D88357 | H. sapiens mRNA for CDC2 delta T |
| AF067656 | H. sapiens ZW10 interactor Zwint mRNA |
| D64110 | H. sapiens mRNA for ANA |
| AJ000186 | H. sapiens mRNA for MAD2 protein |
| U37426 | Human kinesin-like spindle protein HKSP (HKSP) mRNA |
| DNA repair/stability | |
| Y09008 | H. sapiens mRNA for uracil-DNA glycosylase |
| M60527 | Human deoxycytidine kinase mRNA |
| HG4074-HT4344 | Rad2 |
| U39817 | Human Blooms syndrome protein (BLM) mRNA |
| X62534 | H. sapiens HMG-2 mRNA |
| AF029669 | H. sapiens Rad51C (RAD51C) mRNA |
| AC004770 | H. sapiens chromosome 11, BAC CIT-HSP-311e8 (BC269730) containing the hFEN1 gene |
| U03911 | Human mutator gene (hMSH2) mRNA |
| Oncogene/Tumor associated | |
| U76638 | Human BRCA1-associated RING domain protein (BARD1) mRNA |
| Y15227 | H. sapiens mRNA for leukemia-associated gene 1 |
| X64228 | H. sapiens can mRNA |
| AB024704 | H. sapiens mRNA for fls353 |
| Apoptosis | |
| U13737 | Human cysteine protease CPP32 isoform alpha mRNA |
| Transcription regulator | |
| U74612 | Human hepatocyte nuclear factor-3/fork head homolog 11A (HFH-11A) mRNA |
| M62810 | Human mitochondrial transcription factor 1 mRNA |
| U61145 | Human enhancer of zeste homolog 2 (EZH2) mRNA |
| G protein | |
| U57094 | Human small GTP-binding protein mRNA |
| Splicing | |
| AF016371 | H. sapiens U-snRNP-associated cyclophilin (USA-CyP) mRNA |
| AF026402 | H. sapiens U5 snRNP 100 kD protein mRNA |
| Unknown (ESTs) | |
| L38933 | H. sapiens GT198 mRNA |
| AF070552 | H. sapiens clone 24767 mRNA sequence |
| D21063 | Human mRNA for KIAA0030 gene |
| N30625 | H. sapiens cDNA clone IMAGE:257795 3′, mRNA sequence |
| D26018 | Human mRNA for KIAA0039 gene |
| D14657 | Human mRNA for KIAA0101 gene |
| AI525633 | PT1.3_04_A08.r tumor1 Homo sapiens cDNA 5′, mRNA sequence |
| D87448 | Human mRNA for KIAA0259 gene |
| U79241 | Human clone 23759 mRNA |
| AF059274 | H. sapiens neuroglycan C mRNA |
| AW016815 | H. sapiens cDNA clone IMAGE:2709880 3′, mRNA sequence |
| AA203476 | H. sapiens cDNA clone IMAGE:446424 5′, mRNA sequence |
| AI680675 | H. sapiens cDNA clone IMAGE:2272022 3′, mRNA sequence |
RNA levels are expressed relative to the Ad-GFP control and were upregulated 4-fold or higher in two separate DNA microarrays.