Skip to main content
. Author manuscript; available in PMC: 2025 Jul 11.
Published in final edited form as: Chest. 2025 Jan 18;168(1):43–55. doi: 10.1016/j.chest.2024.12.037

Table 3.

Unadjusted correlations between quantitative small airways measures and spirometry

FEV1 p-Value pp FEV1 p-Value FEV1/FVC p-Value
2011, N = 404
 Exp−856 0.011 0.831 −0.112 0.024 −0.446 <0.001
 E/I MLA −0.210 <0.001 −0.232 <0.001 −0.354 <0.001
 RVC−856 to −950 −0.292 <0.001 −0.240 <0.001 −0.232 <0.001
 Residual−856 −0.149 0.003 −0.189 <0.001 −0.410 <0.001
2016, N = 404
 Exp−856 −0.072 0.149 −0.126 0.011 −0.486 <0.001
 E/I MLA −0.292 <0.001 −0.233 <0.001 −0.385 <0.001
 RVC−856 to −950 −0.324 <0.001 −0.220 <0.001 −0.223 <0.001
 Residual−856 −0.216 <0.001 −0.181 <0.001 −0.413 <0.001

Note: Pearson correlation coefficients were reported. p < 0.05 was considered significantly different from zero. Abbreviations: FEV1, Forced Expiratory Volume in the first 1 second; pp FEV1, percent predicted FEV1; FVC, Forced Vital Capacity; Exp−856, percent gas trapping; E/I MLA, expiratory to inspiratory ratio of mean lung attenuation; RVC−856 to −950, relative volume change of voxels with attenuation between −856 HU and −950 HU; Residual−856, residuals from the linear regression of Exp−856 on the percent of voxels with attenuation less than −950 HU.