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. 2025 Jan 18;168(1):43–55. doi: 10.1016/j.chest.2024.12.037

Table 3.

Unadjusted Correlations Between Quantitative Small Airway Measures and Spirometry

Small Airway Measures FEV1 P Value pp FEV1 P Value FEV1/FVC P Value
2011 (n = 404)
 Exp−856 0.011 .831 –0.112 .024 –0.446 < .001
 E/I MLA –0.210 < .001 –0.232 < .001 –0.354 < .001
 RVC−856 to −950 –0.292 < .001 –0.240 < .001 –0.232 < .001
 Residual−856 –0.149 .003 –0.189 < .001 –0.410 < .001
2016 (n = 404)
 Exp−856 –0.072 .149 –0.126 .011 –0.486 < .001
 E/I MLA –0.292 < .001 –0.233 < .001 –0.385 < .001
 RVC−856 to −950 –0.324 < .001 –0.220 < .001 –0.223 < .001
 Residual−856 –0.216 < .001 –0.181 < .001 –0.413 < .001

Data are presetned as Pearson correlation coefficients unless otherwise indicated. P < .05 was considered significantly different from zero. E/I MLA = expiratory-to-inspiratory ratio of mean lung attenuation; Exp−856 = percentage of voxels with attenuation less than -856 HU on expiratory CT scans; HU = Hounsfield unit; pp FEV1 = percent predicted FEV1; Residual–856 = residuals from the linear regression of Exp−856 on the percentage of voxels with attenuation less than –950 HU; RVC−856 to −950 = relative volume change in voxels with attenuation between –856 HU and –950 HU.