Table 3.
Unadjusted Correlations Between Quantitative Small Airway Measures and Spirometry
| Small Airway Measures | FEV1 | P Value | pp FEV1 | P Value | FEV1/FVC | P Value |
|---|---|---|---|---|---|---|
| 2011 (n = 404) | ||||||
| Exp−856 | 0.011 | .831 | –0.112 | .024 | –0.446 | < .001 |
| E/I MLA | –0.210 | < .001 | –0.232 | < .001 | –0.354 | < .001 |
| RVC−856 to −950 | –0.292 | < .001 | –0.240 | < .001 | –0.232 | < .001 |
| Residual−856 | –0.149 | .003 | –0.189 | < .001 | –0.410 | < .001 |
| 2016 (n = 404) | ||||||
| Exp−856 | –0.072 | .149 | –0.126 | .011 | –0.486 | < .001 |
| E/I MLA | –0.292 | < .001 | –0.233 | < .001 | –0.385 | < .001 |
| RVC−856 to −950 | –0.324 | < .001 | –0.220 | < .001 | –0.223 | < .001 |
| Residual−856 | –0.216 | < .001 | –0.181 | < .001 | –0.413 | < .001 |
Data are presetned as Pearson correlation coefficients unless otherwise indicated. P < .05 was considered significantly different from zero. E/I MLA = expiratory-to-inspiratory ratio of mean lung attenuation; Exp−856 = percentage of voxels with attenuation less than -856 HU on expiratory CT scans; HU = Hounsfield unit; pp FEV1 = percent predicted FEV1; Residual–856 = residuals from the linear regression of Exp−856 on the percentage of voxels with attenuation less than –950 HU; RVC−856 to −950 = relative volume change in voxels with attenuation between –856 HU and –950 HU.