Table 2. Review of conversion surgery of AFPGC.

Report	Histological type	Sex	Age	Metastases/Invasion	Preoperative chemotherapy	Surgical procedure	Clinical course	Reported survival
Ye et al. 201330)	HAC	Male	58	Multiple liver metastases tumor thrombosis in the portal vein	4 cycles of epirubicin, oxaliplatin, and fluorouracil 6 cycles of capecitabine and oxaliplatin	Distal gastrectomy with left lateral sectionectomy	No recurrence	20 months (alive)
Becq et al. 201531)	HAC	Male	69	Infiltration into left liver and splenic hilum paraaortic lymph node metastases	4 cycles of epirubicin, oxaliplatin, and capecitabine	Total gastrectomy with splenectomy, left hemihepatectomy, and partial phrenicotomy	No recurrence	31 months (alive)
Nakao et al. 201632)	Unknown	Male	63	Tumor thrombosis in the portal vein	3 cycles of S-1 and cisplatin	Total gastrectomy	No recurrence	48 months (alive)
Shen et al. 201633)	HAC	Male	70	Infiltration into left liver	2 cycles of capecitabine and oxaliplatin	Resection of the stomach and external lobe of left liver	No recurrence	7 months (alive)
Simmet et al. 201834)	HAC	Male	64	Three lesions of liver metastases	6 cycles of cisplatin and etoposide	Gastrectomy and right hemihepatectomy	No recurrence	More than 9 years (alive)
Jun et al. 202335)	GAED	Female	69	Two lesions of liver metastases	18 cycle of nivolmab	Partial hepatectomy	No recurrence	25 months (alive)
Present case	HAC + GAED	Male	71	Six lesions of liver metastases	6 cycles of cisplatin, capecitabine, and trastuzumab	Distal gastrectomy with left lateral sectionectomy and partial hepatectomy	No recurrence	28 months (alive)

GAED, gastric adenocarcinoma with enteroblastic differentiation; HAC, hepatoid adenocarcinoma