Table 3.
Antibacterial and cytotoxic activity of compounds 1–8 from extracts of A. marii FG-Z21
| Anti-bacteria assay | Cytotoxicity | ||||||
|---|---|---|---|---|---|---|---|
| E. faecalis | MRSA | Cell line A549 | |||||
| Zone of inhibition (mm) | MIC (µg/mL) | MBC (µg/mL) | Zone of inhibition (mm) | MIC (µg/mL) | MBC (µg/mL) | IG50 (µg/mL) | |
| 1 | – | – | – | 9.22 ± 0.05 | 16.00 | – | 8.63 |
| 2 | 13.63 ± 0.17 | 8.00 | 16.00 | 10.27 ± 0.30 | 8.00 | 32.00 | 10.46 |
| 3 | – | – | – | 11.15 ± 0.38 | 8.00 | 8.00 | 4.97 |
| 4 | 24.73 ± 0.55 | 2.00 | 4.00 | – | – | – | 83.08 |
| 5 | 18.63 ± 0.52 | 4.00 | 8.00 | 10.21 ± 0.02 | 16.00 | 32.00 | – |
| 6 | 15.08 ± 0.28 | 4.00 | 8.00 | 10.90 ± 0.06 | 8.00 | 16.00 | – |
| 7 | 11.19 ± 0.82 | 4.00 | 16.00 | 11.27 ± 0.13 | 8.00 | 8.00 | – |
| 8 | 14.97 ± 0.35 | 8.00 | 16.00 | – | – | – | – |
| Cisplatin | – | – | – | – | – | – | 4.34 |
| kan | – | – | – | – | – | – | – |
– indicates no antibacterial activity/ cytotoxic activity