Skip to main content
. 2002 Feb 26;99(5):3018–3023. doi: 10.1073/pnas.052703299

Figure 3.

Figure 3

B cells derived from the 1–82 transgenic mice differentiate to mature cells. (A) Splenocytes from control, Ii−/−, and 1–82 heterozygotic (hetero) or homozygotic (homo) mice were double-stained with anti-B220 and either anti-IgM, anti-CD23, or anti-IgD. Histograms show the expression of the various markers on B220-positive cells. (B) Splenocytes from control, Ii−/−, and 1–82 homozygotic mice were triple-stained with anti-B220 and anti-IgD, anti-IgM, anti-CD23, and anti-CD21. Dot plots show the expression of the markers on B220-positive cells. M, mature B cells; T1, transitional B cells 1; T2, transitional B cells 2; MZ, marginal zone B cells. The results presented are representative of five different experiments.