Long-range interactions in the RNase P RNA. (A) Dock between P15.1 (blue) and P5.1 (green). Nucleotides A290, A295, and A296 in P15.1 involved in A-minor interactions with P5.1 are colored in yellow. Nucleotide A291, involved in a long-range cross-strand stacking interaction, is colored in red. (B) Dock between P8 (blue) and P4 (green). Nucleotides A99, A100, A106, and A107 in P8 are involved in A-minor interactions with P4 and are colored in yellow. See supporting information for an expanded view of the secondary structure.