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Sequence alignment of human and mouse Boat and ataxin-1 and their functional domains. Identical and similar residues are shown in black and gray, respectively. The AXH domain, the polyglutamine-repeat tract, and the NBA domain are marked with a blue box, a red line, and a green box, respectively. The region deleted within the previously defined self-association domain of ataxin-1 is underlined with an orange line and is marked as ΔSAR (self-association region) in this study.
